• The development of electrospun chloramphenicol containing wound dressing 

      Murugaiah, Anjanah (Master thesis; Mastergradsoppgave, 2021-05-11)
      Wound healing is among the most complex processes in the human body that is greatly coordinated with a focus to rebuild tissue integrity and restore the skin´s protective barrier. The normal healing process is disrupted in chronic wounds, leading to delayed wound healing due to several underlying factors such as aging, obesity, and diabetes. Among chronic wounds 50 % are infected and up to 78 % of ...
    • Electrospinning of chloramphenicol-containing nanofibrous dressings for treatment of chronic wounds 

      Schulte Werning, Laura; Murugaiah, Anjanah; Skalko-Basnet, Natasa; Holsæter, Ann Mari (Conference object; Konferansebidrag, 2021-03-10)
      <p><i>Background</i> An efficient treatment is crucial to overcome the delayed healing process and high infection rate in chronic wounds. Nanofibrous dressings, having a nano‐sized fiber structure, can enhance cell ingrowth and support the healing process. In addition, nanofibers can deliver active ingredients e.g. antibiotics into the wound to treat wound infection. By incorporating broad‐spectrum ...
    • Multifunctional Nanofibrous Dressing with Antimicrobial and Anti-Inflammatory Properties Prepared by Needle-Free Electrospinning 

      Schulte Werning, Laura; Murugaiah, Anjanah; Singh, Bhupender; Johannessen, Mona; Engstad, Rolf Einar; Skalko-Basnet, Natasa; Holsæter, Ann Mari (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-21)
      An active wound dressing should address the main goals in wound treatment, which are improved wound healing and reduced infection rates. We developed novel multifunctional nanofibrous wound dressings with three active ingredients: chloramphenicol (CAM), beta-glucan (βG) and chitosan (CHI), of which βG and CHI are active nanofiber-forming biopolymers isolated from the cell walls of Saccharomyces ...